Two spirit people are different. They hold a different energy then other people do. It's something that is hardwired into their soul and radiates from their beingness.
I realized over time that I could actually feel the presence of another two-spirit person. While the term "gay" did not always describe the person accurately, there was something about their energy that was distinctly different. The energy of a two-spirit male felt "soft" to me, they didn't have the "hard edge" that other males did. Two-spirit females felt "strong" to me, they had a degree of inner strength about them that most other women did not. It's not about their mannerism, speech or how they looked, it's in the energy that radiates from their soul. I can actually FEEL their two spirits!
Two-spirit people have a balance of male and female energies imbedded in their soul. They can think and feel as a male does and also think and feel as a female does. Their primary mission is to hold the energy of both polarities as one. To merge both the male and female energies into one whole and complete energy that is not lacking or missing anything.
The challenge in this mission is to keep the two energies in balance in the same body. To find the specific balance of male and female energies that works for their particular soul and body. To come to an acceptance of both the male and female qualities in such a way as to bring about harmony and peace within the individual.
Two-spirit people are also an energetic stabilizing force on the planet. At this time the planet is learning how to move from the extremes of duality to the energy of wholeness and balance. Integrating the polarities (good/bad, male/female, light/dark, etc) to a balance where it is not one or the other, but rather both in harmony. Two-spirit people serve as a model and energetic blueprint of balanced and integrated energy. Two-spirit people were given the task to keep their unique combination of male and female energies in balance within their own bodies.
Because two-spirit people were designed to be balanced, it's a natural state rather than something that has to be strenuously sought after and learned. They need to struggle less to find balance in their system, for they were "wired" to achieve balance. For most two-spirit people, simply not resisting the flow of life will automatically bring your system into balance and harmony. Your soul is programmed for balance. While this balance usually does not look like anyone elses "balance," by simply not fighting your internal desires, you will automatically locate the balance that is right for you. Your natural desires will ALWAYS guide you back to balance.
Because two-spirit people can achieve balance more naturally, they also become more open to the spiritual gifts associated with balance. Balance allows two-spirit people to understand, sense, and decode things with a degree of clarity that others cannot easily attain.
The nature of the universe is balance and harmony. So when one is in harmony and in balance they become "attuned" to the fundamental principles that make up the universe. So like a tuning fork, when a person is in balance, they resonate with the balance in the universe which gives them access to spiritual knowledge and understandings that are normally beyond the range of people who are not in balance.
It's for this reason that two-spirit people have a sensitivity towards things that most other people don't have. They are sensitive to subtle energies and attuned to aspects of life that go right by many others. They are more in tuned with natural truths and laws in the universe. So, what is "True" and "Right" is more intuitively obvious. They can see through ineffective cultural beliefs, indoctrination, programming, and religious dogma. They can feel the Truth behind all situations.
They can see through conflicts and feel what is the most harmonious solution and how to create win-win situations. They can feel hidden hurts and buried pain in others along with an intuitive understand on how healing can occur. They have a sensitivity to energies and emotions that allow them to know how others are feeling. Even very subtle shifts in energy are obvious (and sometimes unbalancing) to two-spirit individuals.
Staying Balanced...
Staying balanced is the whole trick behind leading a fulfilling life. When two-spirit individuals are balanced everything seems to flow and is harmonious. When things are not balanced, life can be unpleasant. Here are some tips to keeping yourself balanced:
1. Trust your intuition
You get "knowings" that don't seem to align with what the rest of the world believes. You seem to get messages that contradict the way "everyone else" does things. Learning to trust these spiritual knowings will bring an amazing sense of peace into your life. These knowings are messages to guide *your* progress and may or may not be relevant to others. Listen to your intuition, they are your source of Truth. Also realize that the same information may/may not be true for others. It's for your private use, other people get their own intuition.
2. Your desires always lead you to balance.
Those desires you have are your road map that lead you to balance and harmony. Whether the desire is to explore anal sex or eat ice cream (or even mix the two together?

Following your desires will most rapidly bring your body/soul into balance. When you want to sleep during the middle of the day, or not do something you think you should... that is your desire telling you how to remain in balance. Listening to and following your desires will bring you not only balance, but rapid spiritual progress. Learn to listen and follow your desires... it is the language of your soul.
3. You are sensitive to energy... don't take it personally.
Your sensitivity to energy is far beyond your ability to even comprehend it right now. You often will sense energies and assume they are your thoughts or feelings. They are *usually NOT yours*. They are energies that belong to others that you can detect and feel. Realizing that you do not need to "take these on" as your own will save you much grief. *When you feel disharmonious feelings, emotions and thoughts... they are generally energies left behind from other people.* Notice them, and let them pass. They do not belong to you.
Most times when you feel unbalanced, it is something you took on from another person, it is not yours. If you mentally decide to take it on by claiming it as yours, you then "own it" and will experience it as your own. To release it simply realize it is not yours and mentally let it go. Your natural state is balance and harmony.
Wanting to isolate from others is a natural way to escape the bombardment of other people's energies. Trust your desires to isolate, they are beneficial to your health and balance.
Learn about the laws of energy. Learn how you can release/move/change (transmute) energy.
Learn about energetic modalities of healing that you feel drawn to. Realize all earthbound information comes with a bias. Keep what feels intuitively accurate, discard the rest.
4. You are different.
If you have learned nothing else so far in life, you probably have realized you are different.

In spiritually aware tribes you would have been brought up differently from other children and would be trained by a two-spirit elder. So you would realize your uniqueness. In this culture, you probably were trained to be like everyone else. But you are not.
If you find yourself seeking guidance by looking at what "other people do," you will likely be misguided. Following what other people do is rarely useful for anyone, doubly so for a two-spirit person. Expect your life to look FAR different from other people in this world in every aspect you can possibly imagine... then you wont be disappointed. Putting yourself down by comparing yourself to another person is the most destructive thing you could do to yourself. You are special.